The amidation of aryl halides with alkyl/aryl isocyanides to give the corresponding
amides using polymer-supported palladium–N-heterocyclic carbene complex (PS-Pd-NHC)
as an efficient heterogeneous recyclable catalyst is described. The catalytic system
was optimized with respect to various reaction parameters giving excellent yields
of the desired products. The catalyst can be easily separated by a simple filtration
process and recycled further for up to four consecutive recycle without any loss of
activity and selectivity. The protocol is advantageous due to the ease in handling
of the catalyst, simple workup procedure, phosphine-free, and effective catalyst recyclability.
Key words
amides - heterogeneous catalysis - palladium - cross-coupling - phosphine-free
